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Symptom guide

Burnout

Burnout, prevalent in high-stress professions, often stems from physical factors like adrenal fatigue and imbalances in the HPA axis. It's not just mental; it involves cortisol dysregulation, impacting overall health. An integrative approach focuses on restoring adrenal health, balancing cortisol levels, and adjusting lifestyle factors.

Burnout

Symptoms

  • Emotional Exhaustion: Persistent feelings of energy depletion or exhaustion
  • Depersonalization: A sense of alienation or negativity towards one’s job or personal life
  • Reduced Performance: Decreased productivity or efficacy at work
  • Physical symptoms can also arise, including chronic fatigue, sleep disturbances, headaches, gastrointestinal issues, and increased susceptibility to illnesses due to compromised immunity. From a functional medicine viewpoint, these symptoms are interconnected and indicative of systemic imbalance

Causes

  • In functional medicine, the belief is that burnout arises from an interplay of genetic, environmental, and lifestyle factors. Prolonged exposure to stress is a significant contributor, with the body’s stress response system—the hypothalamic-pituitary-adrenal (HPA) axis—becoming dysregulated over time
  • Prolonged stress leads to chronic elevation of the hormone cortisol. Initially, this helps the body cope with stress, but over time, constant high levels can lead to ‘cortisol resistance,’ similar to how insulin resistance develops in diabetes. When this happens, tissues become less responsive to cortisol, leading to inflammation and a cascade of health issues that contribute to the feeling of burnout
  • Diet, exercise, sleep quality, and exposure to environmental toxins also play critical roles in burnout. Poor nutrition can lead to deficiencies in key vitamins and minerals necessary for energy production and stress management. Lack of exercise, poor sleep, and exposure to toxins can contribute to physical and mental fatigue, exacerbating burnout symptoms

Treatments

  • Nutritional Therapy: A well-balanced diet rich in lean proteins, fruits and vegetables can correct nutrient deficiencies, support energy production, and reduce inflammation. Certain supplements such as B vitamins, magnesium, and adaptogenic herbs may also be recommended
  • Exercise: Regular physical activity can help regulate the HPA axis, lower stress levels, improve mood, and enhance sleep quality
  • Mind-Body Techniques: Practices such as mindfulness, meditation, yoga, and deep breathing can help manage stress, improve mental resilience, and facilitate relaxation
  • Sleep Hygiene: Good sleep hygiene practices are essential for restoring the body’s natural rhythms and healing the adrenal system. This can involve maintaining a regular sleep schedule, reducing exposure to blue light before bed, and creating a sleep-friendly environment
  • Detoxification: Minimizing exposure to environmental toxins and supporting the body’s detoxification processes can also help manage burnout
  • Personal and Professional Balance: A holistic approach to burnout must also address workload and personal life stressors. This could involve time management strategies, setting healthy boundaries, seeking social support, or even professional counseling

Our top pick for Burnout

Curated tests that cover the relevant biomarkers.

Adrenal Stress Test Plus – Cortisol, DHEA-S & ProlactinLab Test

Adrenal Stress Test Plus – Cortisol, DHEA-S & Prolactin

GetTested’s at-home blood collection kit includes lab testing for cortisol, DHEA-S, and prolactin to provide an overview of adrenal function and stress-related hormone patterns. Samples are collected at home and analyzed by a CLIA-certified laboratory, with results delivered digitally.

$129.00
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Adrenal Stress Test – Cortisol & DHEA-SLab Test

Adrenal Stress Test – Cortisol & DHEA-S

Measure key adrenal hormones at home with our at-home blood collection kit and laboratory analysis. This test includes cortisol and DHEA-S, providing a clear overview of these hormone levels. Samples are collected at home, analyzed in a certified laboratory, and results are delivered securely online.

$119.00
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Diurnal Cortisol & CAR TestLab Test

Diurnal Cortisol & CAR Test

GetTested’s Diurnal Cortisol & CAR Test measures cortisol at six time points throughout the day, along with DHEA-S, to provide a detailed view of how cortisol levels change from morning to night. This test is designed to assess the full daily cortisol curve, including the cortisol awakening response (CAR), and may be relevant when exploring factors such as fatigue, stress, sleep patterns, or daily energy variation. Collected at home using saliva, the samples are analyzed in a CLIA-certified laboratory, with results delivered digitally. Approved for New York residents.

$209.00
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4-Point Cortisol TestLab Test

4-Point Cortisol Test

GetTested’s 4-Point Cortisol Test measures cortisol at four time points throughout the day to assess your diurnal rhythm. Cortisol follows a daily pattern that influences energy, sleep, and the body’s response to stress. Measuring levels at multiple time points provides a more complete picture than a single measurement. Samples are collected at home using a saliva method and analyzed in a certified laboratory, with results delivered digitally. Approved for New York residents.

$159.00
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When to see a doctor

At-home testing is a screening tool, not a diagnosis. If symptoms are severe, sudden, or worsening, contact a healthcare provider.

Accredited labs

Processed in ISO 15189 / 17025 facilities.

Validated assays

Performance-tested against clinical references.

500,000+ customers

Trusted across the EU, UK and US.

At-home collection

Simple kits with step-by-step instructions.

Discreet shipping

Generic packaging, tracked end-to-end.

Clinician-reviewed

Reports reviewed by qualified clinicians.

CLIA-certified & secure

Secure data handling, CLIA-certified labs.

Retest promise

Sample issue? We make it right.

Accredited labs

Processed in ISO 15189 / 17025 facilities.

Validated assays

Performance-tested against clinical references.

500,000+ customers

Trusted across the EU, UK and US.

At-home collection

Simple kits with step-by-step instructions.

Discreet shipping

Generic packaging, tracked end-to-end.

Clinician-reviewed

Reports reviewed by qualified clinicians.

CLIA-certified & secure

Secure data handling, CLIA-certified labs.

Retest promise

Sample issue? We make it right.

Frequently asked questions

Ready when you are

Take the first step toward knowing your body.

At-home sample collection, accredited labs, and expert-reviewed results — built around your life, not a waiting room.

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