Female Hormone Test (Large)

About this test

How It Works

You collect saliva samples at home, including a morning sample taken 30 minutes after waking. The samples are then sent to a CLIA-certified laboratory for analysis, and your results are delivered digitally once testing is complete.

Saliva Collection

The test uses saliva samples collected at home.

This non-invasive method allows for hormone measurements at specific time points, including the morning cortisol sample, which reflects the early part of the body’s daily rhythm.

Morning Cortisol Measurement

Cortisol measured 30 minutes after waking reflects the early morning response, an important part of the body’s daily rhythm.

This measurement provides additional context to how the body responds to stress and how cortisol levels change at the start of the day.

Estrogen Patterns and Hormone Balance

In addition to progesterone, testosterone, DHEA-S, and cortisol, this test measures three forms of estrogen: estradiol (E2), estrone (E1), and estriol (E3).

Evaluating these together provides insight into how estrogen levels vary in relation to overall hormone balance and across different stages of life.

Preparation Instructions

Collect your samples according to the instructions provided in your kit.

Avoid eating, drinking (except water), brushing teeth, or smoking at least 30 minutes before each collection.

Who Should Consider This Test

This test is relevant for individuals who want a comprehensive overview of hormone levels across reproductive and stress-related systems.

It may be particularly useful when exploring factors such as fatigue, stress, mood changes, sleep disturbances, or hormonal changes across different life stages, including perimenopause and menopause.

Understanding CLIA Certification

Your samples are analyzed in a CLIA-certified laboratory, ensuring that testing is performed according to established U.S. quality standards using validated methods.

Biomarkers included

• Estradiol (E2): Estradiol is the most biologically active form of estrogen in the body. It plays a central role in reproductive health, regulating the menstrual cycle, ovulation, and fertility. Estradiol also affects bone density, cardiovascular health, brain function, and metabolism. Levels vary throughout the menstrual cycle and across different life stages such as puberty, pregnancy, and menopause. Measuring e
• Testosterone: Testosterone is the primary male sex hormone, although it is also produced in smaller amounts in women. It plays a crucial role in male reproductive development, muscle mass, bone density, and sex drive. In women, testosterone contributes to libido, muscle mass, and bone health. Imbalances can lead to various issues, including decreased libido, erectile dysfunction (in men), fatigue, loss of muscl
• DHEA-S: DHEA-S is a hormone produced mainly by the adrenal glands and serves as a precursor to sex hormones, including androgens and estrogens. Compared with DHEA, DHEA-S is more stable in the bloodstream and is therefore commonly measured to evaluate adrenal androgen production. Levels typically peak in early adulthood and gradually decline with age. Elevated DHEA-S may be seen in conditions associated w
• Progesterone: Progesterone is a female sex hormone primarily produced by the ovaries after ovulation and by the placenta during pregnancy. It plays a crucial role in preparing the uterus for pregnancy, maintaining pregnancy, and regulating the menstrual cycle. Progesterone levels naturally fluctuate throughout the menstrual cycle. Low levels can lead to irregular periods, difficulty conceiving, or complications
• Cortisol: Cortisol is a steroid hormone produced by the adrenal glands, known as the body's primary stress hormone. It plays a crucial role in regulating metabolism, immune response, and blood pressure, making its levels important for assessing stress response and adrenal function.
• Estriol (E3): Estriol is a naturally occurring estrogen and the weakest of the three primary estrogens. It is produced in small amounts in non-pregnant individuals but becomes the dominant estrogen during pregnancy, as it is generated through interactions between the placenta and the fetus. Estriol reflects aspects of estrogen metabolism and hormone turnover. Measuring estriol can help provide a broader picture
• Estrone (E1): Estrone is one of the three main forms of estrogen produced in the body. It is synthesized primarily from androgens in fat tissue and becomes the dominant estrogen after menopause. Estrone can be converted into estradiol or further metabolized into various estrogen metabolites. Measuring estrone helps provide insight into overall estrogen production and balance, particularly in relation to age, bo

How to prepare

For morning cortisol, collect 30 min after waking. Avoid eating, drinking (other than water), brushing teeth, or strenuous exercise for 30-60 min prior to collection. Detailed instructions are provided with the test kit.

Frequently asked questions

How accurate are at-home saliva hormone tests compared to blood tests?

When performed using advanced methods like LC-MS in CLIA-certified labs, salivary hormone tests are highly accurate for measuring bioavailable hormone levels. Saliva provides insight into the unbound hormones active at the cellular level, particularly relevant for an at home hormone test.

What hormones does this saliva hormone test measure, and why are they important?

This test measures Estradiol (E2), Estriol (E3), Estrone (E1), Progesterone, Testosterone, DHEA-S, and morning Cortisol. These hormones are crucial for reproductive health, mood, energy, stress response, and overall well-being, and understanding them is key to addressing potential hormone imbalance symptoms.

How do I collect the saliva sample correctly for this at home hormone test, and what should I avoid before testing?

Detailed instructions are provided. For morning cortisol, collect 30 min after waking. Avoid eating, drinking (other than water), brushing teeth, or strenuous exercise for 30-60 min prior to collection. This ensures accurate results for your cortisol test at home saliva.

What is LCMS hormone testing saliva, and why is it used for hormone analysis?

LCMS (Liquid Chromatography-Mass Spectrometry) is a highly accurate and sensitive laboratory method used to precisely identify and quantify hormones. It's considered a gold standard for salivary hormone analysis due to its specificity and ability to detect low concentrations, ensuring reliable results for bioavailable hormones in an at home hormone test like this.

Customer reviews

4.6/5 (5)

• 4/5 — This test gave me a helpful snapshot of my hormone levels. It's a good starting point for further discussions with my doctor.
• 5/5 — The whole process was so discreet and easy to manage from my own home. Definitely a great option.
• 4/5 — I appreciated getting my hormone levels checked from home. The digital results came back quickly, which was a plus.
• 5/5 — This at-home test was incredibly easy to use. The instructions were clear and the process was straightforward.
• 5/5 — After experiencing symptoms for a while, this test provided the clarity I needed. Highly recommend for anyone curious about their hormones.