Spermine is a polyamine derived from spermidine that plays a crucial role in stabilizing DNA, RNA, and cellular membranes. It contributes to antioxidant defense, inflammation regulation, and the control of cellular aging. Elevated levels can occur during periods of high metabolic or regenerative activity, while low levels may indicate reduced polyamine synthesis or increased cellular stress. Balanced spermine levels support optimal cellular integrity and protection against premature aging.
Spermine is a polyamine derived from spermidine that plays a vital role in stabilizing DNA, RNA, and cellular membranes. It supports antioxidant defenses, regulates inflammation, and contributes to cellular repair and longevity.
Higher spermine levels may occur during periods of increased metabolic or regenerative activity. In some cases, elevated levels can also indicate a compensatory response to oxidative stress or tissue repair processes.
Low levels may indicate decreased polyamine synthesis, nutrient deficiencies, or impaired cellular regeneration. They can also occur due to chronic oxidative stress or age-related declines in metabolic function.
Supporting polyamine metabolism through balanced nutrition, regular physical activity, and adequate intake of polyamine precursors (such as arginine, methionine, and B vitamins) helps maintain optimal levels. Reducing oxidative stress and supporting mitochondrial health further enhance cellular stability.