Desulfomonas pigra is a species of sulfate-reducing bacteria (SRB) found in anaerobic environments, including the human gut. It plays a role in sulfur metabolism by reducing sulfate to hydrogen sulfide (H₂S). While hydrogen sulfide is a naturally occurring compound in the colon, elevated levels produced by SRBs like D. pigra can disrupt intestinal barrier function and contribute to gastrointestinal inflammation or discomfort. Increased abundance of Desulfomonas pigra may indicate an overgrowth of sulfur-reducing microbes, potentially associated with diets high in sulfur-containing foods or imbalances in gut microbiota.
It is a sulfate-reducing bacterium in the gut that generates hydrogen sulfide as part of its metabolism.
To assess the levels of sulfur-reducing bacteria that may play a role in gut dysbiosis or inflammation.
It could suggest an overactive sulfur metabolism in the gut and a possible imbalance in the microbial community.
In high amounts, it can produce excessive hydrogen sulfide, which may damage the gut lining and trigger inflammation.