RHOBTB2 (Rho-related BTB domain-containing protein 2): RHOBTB2 is a gene that encodes a protein belonging to the Rho family of small GTPases, which regulate cytoskeletal dynamics, cell migration, and cell cycle progression. The additional BTB domain indicates roles in protein-protein interactions and regulatory functions beyond traditional Rho signaling. RHOBTB2 may affect cell proliferation, apoptosis, intracellular trafficking, mitochondrial function, and responses to oxidative stress.