Bilophila wadsworthii
Bilophila wadsworthii is a gram-negative, anaerobic, sulfur-reducing bacterium commonly present in small amounts in the human gut. It can metabolize bile acids and reduce sulfur compounds to hydrogen sulfide (H₂S), a gas that, in excessive quantities, can be toxic to gut epithelial cells and disrupt intestinal integrity. Increased levels of Bilophila wadsworthii have been linked to inflammatory conditions like colitis and may signal a dysbiotic gut environment, particularly in response to high-fat or high-animal protein diets. This bacterium is considered a potential pathobiont due to its ability to trigger inflammation under certain circumstances.
Description
It's a sulfur-reducing bacterium in the gut microbiome that can metabolize bile and produce hydrogen sulfide gas.
To evaluate the levels of sulfur-reducing bacteria, which may affect gut health and inflammation.
It may indicate dysbiosis, a high sulfur intake, or an inflammatory condition in the gut.
When present in excess, it can lead to mucosal damage and inflammation, especially in individuals who are susceptible or consume diets high in fat and sulfur.
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