Beta-glucuronidase is an enzyme produced by certain gut bacteria that can break the bond between glucuronic acid and various toxins, hormones, or drugs that the liver has prepared for elimination. Elevated beta-glucuronidase activity in stool may indicate a microbial imbalance and can interfere with detoxification by reactivating substances like estrogen and xenobiotics in the colon. This reactivation may contribute to systemic toxicity or hormonal imbalances. Measuring beta-glucuronidase in stool helps assess microbial metabolism and detoxification efficiency in the gut.
It’s an enzyme produced by specific gut bacteria that can undo the detoxification process by breaking the bond between toxins and glucuronic acid.
To assess how gut microbes might influence the body’s ability to eliminate hormones, drugs, and toxins.
It may indicate a microbial imbalance and a risk of reactivating harmful substances in the gut.
Yes, especially estrogen, since the enzyme can release it back into circulation from the gut.
Gut microbial composition, diet, toxin exposure, and certain medications can influence enzyme levels.